<b>httk</b>: <i>R</i> Package for High-Throughput Toxicokinetics 论文
2017Journal of Statistical Software引用 304顶会
Computational Drug Discovery MethodsAnimal testing and alternativesEffects and risks of endocrine disrupting chemicals
摘要
Thousands of chemicals have been profiled by high-throughput screening programs such as ToxCast and Tox21; these chemicals are tested in part because most of them have limited or no data on hazard, exposure, or toxicokinetics. Toxicokinetic models aid in predicting tissue concentrations resulting from chemical exposure, and a