Vital Trace: Protocol-Constrained Patient-State Reasoning for Longitudinal Clinical Trajectories 文章

arXiv:2602.12833v2 Announce Type: replace-cross Abstract: Longitudinal clinical reasoning over electronic health records requires tracking evolving physiological measurements, laboratory results, and interventions across extended patient trajectories. Existing LLM-based clinical reasoning systems often rely on repeatedly serializing patient histories or exchanging unconstrained textual agent messages, leading to context drift, unstable reasoning, and growing inference cost over long horizons. We present Vital Trace, a protocol-constrained multi-agent framework for future clinical risk prediction over evolving ICU trajectories. Instead of maintaining unbounded textual histories, Vital Trace uses a compact persistent patient-state memory together with staged reasoning performed by four coordinated agents: a Router, Reasoner, Auditor, and Steward.