Multi-Persona Debate System for Automated Scientific Hypothesis Generation 文章

arXiv:2605.23917v1 Announce Type: new Abstract: Modern scientific discovery is bottlenecked not by data scarcity, but by the inability to synthesize fragmented knowledge into actionable hypotheses. This challenge is especially acute in battery materials research, where electrochemical performance, interfacial behavior, and manufacturing feasibility must be optimized simultaneously. Here, we present the Multi-Persona Debate System (MPDS), a literature-grounded framework for automated scientific hypothesis generation that combines literature retrieval, long-context large language model reasoning, corpus-driven persona induction, and structured multi-agent debate. MPDS constructs literature snapshots of up to 500 papers, grounds agents in role-specific evidence pools, and conducts a three-round citation-aware debate followed by moderator synthesis, enabling negotiation between personas while preserving evidence traceability.