Co-folding model guided by structural proteomics 事件

Co-folding model guided by structural proteomics arXiv:2605.26192v1 Announce Type: cross Abstract: Protein structure generative models excel at predicting single protein static structures from sequence, but routinely fail to capture the correct conformational state of protein complexes, critical for protein design and induced proximity modalities such as antibodies and PROTACs. While structural proteomics techniques like Cross-Linking Mass Spectrometry (XL-MS) and Hydrogen-Deuterium Exchange (H