Enhancing Protein-Protein Interaction Prediction with Hierarchical Motif-based Multimodal Protein Embedding 事件

REGULATION2026-06-03影响: MEDIUM

Enhancing Protein-Protein Interaction Prediction with Hierarchical Motif-based Multimodal Protein Embedding arXiv:2606.02629v1 Announce Type: cross Abstract: Protein-protein interactions (PPIs) are essential for many biological processes. However, existing PPI prediction approaches suffer from two major limitations: they overlook the hierarchical organization of proteins, particularly meso-scale motifs that critically regulate PPIs, and fail to effectively integrate sequence, structure, and fun