The Dark Regulome: Disentangling Predictability from Regulation in Genomic Foundation Models 事件

The Dark Regulome: Disentangling Predictability from Regulation in Genomic Foundation Models arXiv:2606.06834v1 Announce Type: new Abstract: High-grade gliomas integrate into neural circuits through functional synapses with neurons, raising the question of which noncoding elements shape synaptogenic gene expression in tumor cells. The regulatory program written across the dark genome, what we call the $\textit{dark regulome}$, is the natural substrate to probe, and sequence foundation models of