The promise and peril of chemical probes 论文

2015Nature Chemical Biology引用 844
Click Chemistry and ApplicationsChemical Synthesis and AnalysisComputational Drug Discovery Methods

摘要

Chemical probes are powerful reagents with increasing impacts on biomedical research. However, probes of poor quality or that are used incorrectly generate misleading results. To help address these shortcomings, we will create a community-driven wiki resource to improve quality and convey current best practice.