Molecular obesity, potency and other addictions in drug discovery 论文

2011MedChemComm引用 352

Computational Drug Discovery MethodsSynthesis and biological activityNuclear Receptors and Signaling

Computational Drug Discovery Methods Nuclear Receptors and Signaling Synthesis and biological activity

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Molecular Obesity is the tendency for lead optimisation to yield candidate molecules that are unfit for their continued survival towards becoming a drug. Reasons for this and other issues are discussed.

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Michael M. Hann

Molecular obesity, potency and other addictions in drug discovery 论文

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