DnaSP, DNA sequence polymorphism: an interactive program for estimating population genetics parameters from DNA sequence data 论文

1995Computer applications in the biosciences引用 249
Algorithms and Data CompressionGene expression and cancer classificationGenetics, Bioinformatics, and Biomedical Research

摘要

DnaSP, DNA sequence polymorphism, is an interactive computer program for the analysis of DNA polymorphism from nucleotide sequence data. The program, addressed to molecular population geneticists, calculates several measures of DNA sequence variation within and between populations, linkage disequilibrium parameters and Tajima's D statistic. The program, which is written in Visual Basic v. 3.0 and runs on an IBM-compatible PC under Windows, can handle a large number of sequences of up to thousands of nucleotides each. Selected region: 1-1524 Number of sites: 1524 Non-Informative Polymorphisms were considered Sites segregating for three or four nucleotides were not considered Number of polymorphic sites analysed 53 Number of pairwise comparisons: 1378 Number of significant pairwise compaiisons by Fisher's exact test: 26 Number of significant pairwise comparisons by chi-square test: 104