Characterization of Nucleic Acids by Nanopore Analysis 论文

详细信息

发表期刊/会议

Accounts of Chemical Research

发表日期

2002-09-27

发表年份

2002

摘要

Single-stranded DNA and RNA molecules in solution can be driven through a nanoscopic pore by an applied electric field. As each molecule occupies the pore, a characteristic blockade of ionic current is produced. Information about length, composition, structure, and dynamic motion of the molecule can be deduced from modulations of the current blockade.