Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors 论文

2020Science引用 3410
Computational Drug Discovery MethodsEnzyme Structure and FunctionSARS-CoV-2 and COVID-19 Research

摘要

The pharmacokinetic characterization of the optimized inhibitor reveals a pronounced lung tropism and suitability for administration by the inhalative route.