David B. Solit 人物
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RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)
2011Nature引用 1435
The RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective manner
2010Proceedings of the National Academy of Sciences引用 447
V600E B-Raf requires the Hsp90 chaperone for stability and is degraded in response to Hsp90 inhibitors
2005Proceedings of the National Academy of Sciences引用 310
Resistance to BRAF Inhibition in Melanomas
2011New England Journal of Medicine引用 242
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