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Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-β论文
Scientific Reports2018引用: 360
Lipophilic Efficiency as an Important Metric in Drug Design论文
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Drug–Target Kinetics in Drug Discovery论文
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Predicting a Drug’s Membrane Permeability: A Computational Model Validated With <i>in Vitro</i> Permeability Assay Data论文
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ADME Properties Evaluation in Drug Discovery: Prediction of Caco-2 Cell Permeability Using a Combination of NSGA-II and Boosting论文
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Cell permeability beyond the rule of 5论文
Advanced Drug Delivery Reviews2016引用: 289
Recent Structural Insights into Cytochrome P450 Function论文
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Prediction of drug–ABC-transporter interaction — Recent advances and future challenges论文
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Predicting Clearance Mechanism in Drug Discovery: Extended Clearance Classification System (ECCS)论文
Pharmaceutical Research2015引用: 308
In vitro Development of Chemotherapy and Targeted Therapy Drug-Resistant Cancer Cell Lines: A Practical Guide with Case Studies论文
Frontiers in Oncology2014引用: 315
CNS Drug Design: Balancing Physicochemical Properties for Optimal Brain Exposure论文
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Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies论文
Scientific Reports2014引用: 365
PharmGKB: The Pharmacogenomics Knowledge Base论文
Methods in molecular biology2013引用: 360
Comparability of Mixed IC50 Data – A Statistical Analysis论文
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Exploration of the medical periodic table: towards new targets论文
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Role of Metal Ions in the Self-assembly of the Alzheimer’s Amyloid-β Peptide论文
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