Deepdive-llama3-from-scratch产品(therealoliver/Deepdive-llama3-from-scratch)
Achieve the llama3 inference step-by-step, grasp the core concepts, master the process derivation, implement the code.
Jupyter NotebookMIT★ 629
Activation pathway of a G protein-coupled receptor uncovers conformational intermediates as targets for allosteric drug design论文
Nature Communications2021引用: 220
GPCRdb in 2021: integrating GPCR sequence, structure and function论文
Nucleic Acids Research2020引用: 372
Angiotensin Analogs with Divergent Bias Stabilize Distinct Receptor Conformations论文
Cell2019引用: 290
The Molecular Basis of G Protein–Coupled Receptor Activation论文
Annual Review of Biochemistry2018引用: 1.2K
GPCRdb in 2018: adding GPCR structure models and ligands论文
Nucleic Acids Research2017引用: 555
Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling论文
Cell2015引用: 675
The GPCR Network: a large-scale collaboration to determine human GPCR structure and function论文
Nature Reviews Drug Discovery2012引用: 317
Strategies to Discover Unexpected Targets for Drugs Active at G Protein–Coupled Receptors论文
The Annual Review of Pharmacology and Toxicology2011引用: 216
How and why do GPCRs dimerize?论文
Trends in Pharmacological Sciences2008引用: 215
The evasive nature of drug efficacy: implications for drug discovery论文
Trends in Pharmacological Sciences2007引用: 351
High-Resolution Crystal Structure of an Engineered Human β <sub>2</sub> -Adrenergic G Protein–Coupled Receptor论文
Science2007引用: 3.3K
Structure-based Drug Discovery Using GPCR Homology Modeling: Successful Virtual Screening for Antagonists of the Alpha1A Adrenergic Receptor论文
Journal of Medicinal Chemistry2005引用: 232
Ligand-selective receptor conformations revisited: the promise and the problem论文
Trends in Pharmacological Sciences2003引用: 319
International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on Terms and Symbols in Quantitative Pharmacology论文
Pharmacological Reviews2003引用: 656
Protein‐based virtual screening of chemical databases. II. Are homology models of g‐protein coupled receptors suitable targets?论文
Proteins Structure Function and Bioinformatics2002引用: 296
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