Managing the challenge of chemically reactive metabolites in drug development 论文

2011Nature Reviews Drug Discovery引用 453
DOI
Drug-Induced Hepatotoxicity and ProtectionPharmacogenetics and Drug MetabolismComputational Drug Discovery Methods
Computational Drug Discovery MethodsPharmacogenetics and Drug MetabolismDrug-Induced Hepatotoxicity and Protection
相关技术:Computational Drug Discovery Methods
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Managing the challenge of chemically reactive metabolites in drug development · 作者

B

B. Kevin Park

T

Thomas A. Baillie

I

Ian D. Wilson

D

Dominic P. Williams

N

Nico Vermeulen

D

Donald Tweedie

D

Dennis A. Smith

P

Philip A. Routledge

R

R. Scott Obach

D

Deborah A. Nicoll‐Griffith

S

Sidney D. Nelson

D

Dean J. Naisbitt

H

Hugh Laverty

C

Craig Lambert

J

J. Gerry Kenna

D

David Jones

C

Christopher E. Goldring

S

Stephen E. Clarke

A

Alan R. Boobis