foldingdiff产品(microsoft/foldingdiff)
Diffusion models of protein structure; trigonometry and attention are all you need!
Jupyter NotebookMIT★ 568
HRNet-Semantic-Segmentation产品(HRNet/HRNet-Semantic-Segmentation)
The OCR approach is rephrased as Segmentation Transformer: https://arxiv.org/abs/1909.11065. This is an official impleme...
Python★ 3.3K
Hydrophilic or Lipophilic Statins?论文
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Statins and the COVID-19 main protease: in silico evidence on direct interaction论文
Archives of Medical Science2020引用: 271
Repositioning of the global epicentre of non-optimal cholesterol论文
Nature2020引用: 288
Diabetes and lipid metabolism论文
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PCSK9论文
Circulation Research2018引用: 282
The role of statins in both cognitive impairment and protection against dementia: a tale of two mechanisms论文
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Cognitive Function in a Randomized Trial of Evolocumab论文
New England Journal of Medicine2017引用: 477
PCSK9 is a critical regulator of the innate immune response and septic shock outcome论文
Science Translational Medicine2014引用: 368
Meta-Analysis of Impact of Different Types and Doses of Statins on New-Onset Diabetes Mellitus论文
The American Journal of Cardiology2013引用: 307
Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH论文
EMBO Reports2011引用: 235
Statins as Neuroprotectants: A Comparative In Vitro Study of Lipophilicity, Blood-Brain-Barrier Penetration, Lowering of Brain Cholesterol, and Decrease of Neuron Cell Death论文
Journal of Alzheimer s Disease2011引用: 246
Pravastatin and cognitive function in the elderly. Results of the PROSPER study论文
Journal of Neurology2009引用: 287
Drug Discovery Using Chemical Systems Biology: Identification of the Protein-Ligand Binding Network To Explain the Side Effects of CETP Inhibitors论文
PLoS Computational Biology2009引用: 255
Pleiotropic effects of statin therapy: molecular mechanisms and clinical results论文
Trends in Molecular Medicine2008引用: 592
Molecular biology of PCSK9: its role in LDL metabolism论文
Trends in Biochemical Sciences2007引用: 616
The Crystal Structure of PCSK9: A Regulator of Plasma LDL-Cholesterol论文
Structure2007引用: 241
Safety and Efficacy of Statins in Asians论文
The American Journal of Cardiology2006引用: 270
Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: Drug–drug interactions and interindividual differences in transporter and metabolic enzyme functions论文
Pharmacology & Therapeutics2006引用: 572
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